Given the possible expansion [22, 23] and bearing in mind the immunosuppressive weight of dBMA Tregs (CD4+/CD45RA-/CD25high/CD127low) which finally favor AML cells [7, 19], we investigated the possible correlation of dBMA Tregs with the outcome and obtained the ROC curve optimal cut-off value to predict a better OR (≥21/μL, Figure 2(c)) and OS (Figure 2(d)). This evidence concerns the gene CD4 and acute myeloid leukemia.