IGF1 and anxiety disorder: Although limitations of NESDA need to be accounted for, including that persons with a depressive and/or anxiety disorder were overrepresented, no measures of PTSD were done in the baseline study and other, maybe more relevant stress vulnerability measures were not included, we consider that these data, in conjunction with the results in mice allow us to suggest that measurement of serum IGF-I may help in the clinical assessment of susceptibility to stress.