Remarkably, three genes (Pf.H2B, Pf.GAPDH, and Pf.TRP1) had expression that was higher than Pf.CSP throughout the course of the transmission stage of the parasite with Pf.H2B demonstrating the highest level of expression; Pf.H2B (4,620,000) had 2.85 fold more mRNA transcripts than Pf.CSP (1,620,000) on day 8 post-infection. Here, H2BC21 is linked to infection.