MiRNA prediction indicated that 61 miRNAs have binding sites in both human HER2 and HER3 3’UTRs (Additional file 4: Table S4), among which miR-125-5p, miR-27a-5p, and miR-378 ranked in the top 100 in miRNA abundance in breast invasive carcinoma (TCGA). The gene discussed is ERBB3; the disease is invasive breast carcinoma.