Among different leukemia subtypes, Wee1 was significantly higher in BCR-ABL1-negative samples (diagnosis p = 0.0061; relapse p = 0.005) than in BCR-ABL1-positive samples (diagnosis ns; relapse p = 0.01) compared with normal MNCs (Fig. 1b) (Additional file 1: Table S1). The gene discussed is WEE1; the disease is leukemia.