SHANK3 and infection: Immunoblot analysis of synaptosomal fractions (Fig. 2) from infected (n = 4) and non-infected (n = 8) animals revealed for EAAT2, GluA2, Shank3, and GABAAR α1 a highly significant main effect of infection status (F1,10 = 12.93; p = 0.005, two-way repeated measures ANOVA with protein as a within-subject factor and infection status as a between-subject factor) while no significant effect of protein or interaction was observed (all p > 0.804).