We next used a monoclonal α-Env antibody (HERM-1811-5, Austral Biologicals), recognizing the HML-2 Env C-terminus (for instance, see [72–75]), to assess Env protein expression in ALS and normal spinal cord, motor cortex, cerebellum and frontal cortex samples. Here, ERVW-1 is linked to amyotrophic lateral sclerosis.