CLEC10A and amyotrophic lateral sclerosis: To expand upon previously published reports linking HERV-K(HML-2) with ALS, in the present study we applied our recently optimized strategy [17, 30] for identification of transcribed HML-2 loci to profile transcription of HML-2 loci in various tissue samples from mostly sALS or ALS of unknown etiology and control individuals using three different RT-PCR amplicons within the HML-2 proviral sequence.