Next, target genomic capturing and next-generation sequencing for a panel of 127 genes related to hereditary hearing loss, which included the GJB2, GJB6, SLC26A, MTRNR1, and MTTS1 genes, were conducted to screen for the causative gene variant (s) of deafness in this family (see Additional file 1: Table S1 and Additional file 2: Table S2). This evidence concerns the gene MT-RNR1 and deafness.