As presented in Table 5, patients with SCC had higher frequencies of DAPK1 promoter hypermethylation than those with AdC (OR = 3.53, P < 0.001, Figure S2); DAPK1 promoter hypermethylation was significantly correlated with advanced International Federation of Gynecology and Obstetrics (FIGO) stage of CC (OR = 2.15, P = 0.003, Figure S3), but not with histological grade, lymph node metastasis, HPV infection, age at diagnosis, and therapeutic responses. Here, DAPK1 is linked to metastatic malignant neoplasm in the lymph nodes.