The silencing of DAPK1 by promoter hypermethylation has been long linked to CC, but the established data showed a varied range of DAPK1 promoter hypermethylation rates (24–100%) in cancer tissues (Chaopatchayakul et al., 2010; Missaoui et al., 2011) and inconsistent association results. Here, DAPK1 is linked to cancer.