JAG1 and colorectal carcinoma: Importantly, we further analyzed Dll4 levels in a subset of CRC samples and found that ten out of 11 tumors that were characterized as ICN1 high/JAG1 low contained high levels of Dll4, nine of them being MFNG positive (Supplementary Table 3), further supporting that tumors expressing MFNG may induce Notch1 through Dll4.