TNNI3 and familial dilated cardiomyopathy: For example, phosphorylation of TnI was found rather high in a number of DCM samples where a mutation was found as the cause of the disease: TNNI3 p.98trunc and TNNT2 p.K217del (~2 mol Pi/mol TnI) [78], ACTC E99K (HCM mutation, 1.61 mol Pi/mol TnI) [95], TNNC1 G159D (1.53 mol Pi/mol TnI) [81], and TNNT2 K280N (1.4–1.6 mol Pi/mol TnI).