Increased expression of EGFL7 has been described for tumors of various origins (Diaz et al, 2008; Wu et al, 2009; Huang et al, 2010; Fan et al, 2013; Luo et al, 2014; Khella et al, 2015); therefore, we wondered about the influence of high EGFL7 levels on experimental glioma growth. This evidence concerns the gene EGFL7 and glioma.