Elevated expression of EGFL7 may still be detected in angiogenic vessels during tissue repair or regeneration (Nikolic et al, 2010) as well as in several tumor types, including colon (Diaz et al, 2008), gastric (Luo et al, 2014), breast (Fan et al, 2013), kidney (Khella et al, 2015), liver (Wu et al, 2009), and brain tumors (Huang et al, 2010). This evidence concerns the gene EGFL7 and brain neoplasm.