CSF2 and thrombocytosis disease: Of the 17 patients randomised to GM-CSF, 4 received less than two doses of study drug (1 died before any administration of study drug and 3 triggered safety criteria for study drug termination (defined in the online supplemental data section, table S3); of these 3, 1 had thrombocytosis before any administration of study drug, 1 developed significant transaminitis after one dose, and 1 developed thrombocytopenia after one dose).