The UCSF criteria (1 nodule ≤ 6.5 cm or n ≤ 3 nodules ≤ 4.5 cm or total sum ≤ 8 cm) [27]; the up to seven criteria (number of nodules + the maximum size of the tumour without vascular invasion should be 7 at maximum) [28]; and the AFP score, taking into account the size, number of nodules and the level of AFP (applied in France) [24]. This evidence concerns the gene AFP and neoplasm.