In this study, we determined the estimated rate of CD4+ T-cell decline, the proportion reaching immunological failure, defined as CD4+ T-cell count <200 cells/μl, or initiation of ART, and the estimated time from infection to immunologic failure among MSM infected with HIV subtype B, CRF01_AE, and B/CRF01_AE recombinant strains. Here, CD4 is linked to infection.