This COL3A1 variant has not been reported in any other cases of hEDS and is noted in the ClinVar database as EDS, Nonvascular variant [NM_000090.3(COL3A1):c.2410G>A (p.Gly804Ser)] (https://www.ncbi.nlm.nih.gov/clinvar/variation/17221/). This evidence concerns the gene COL3A1 and Ehlers-Danlos syndrome, hypermobility type.