CD274 and colorectal cancer: Although no study has examined the potential modifying effect of platelet count in this setting, a recent study revealed that postdiagnosis aspirin use was associated with better survival among patients with PD‐L1‐negative/low colorectal cancer, but not among patients with PD‐L1‐high tumors.21 In that context, the effects of aspirin on the metastatic process may depend on the inhibition of platelet function,22 which would also support the effect of platelet count on the prognostic value of PD‐L1 expression.