The available data concerning cancer cells derived from the nervous system show that 100 ng/mL ≈ 66.86 nM of the (VGVAPG)3 peptide strongly upregulated MMP-2 mRNA expression in the rat astrocytoma cell line C6 and human gliomas, such as CB74, CB109 and CB191 (Coquerel et al. 2009). Here, MMP2 is linked to central nervous system cancer.