KLK3 and posterior cortical atrophy: However, this association between cadmium exposure and PSA levels disappears at higher levels of dietary zinc intake.76 During the 7-year follow-up period in the PCPT study,17 dietary and total zinc intake decreased the susceptibility to develop total symptomatic BPH incidence among the placebo population in the second, fourth, and fifth quintiles.17 In the VITAL study, Gonzalez and associates showed that dietary zinc intake over a 10-year period had a non-significant decrease in overall PCa and advanced disease (regional/distant) mortality risk.77