After SE infection, several up-regulated unique DEGs were mainly related to immune function, such as FOS, SOCS1, IL-18, IKBKB, CXCR4, CTAL4, IL10RA, IL10RB, IL1RAP, and AVD. These findings differ from the splenic results after Salmonella infection (Matulova et al., 2012), although they did identify AVD and immune responsive gene 1 (IRG1). This evidence concerns the gene IL18 and Salmonella Infections.