Su et al. found significant increases of several serum cytokines [tumor necrosis factor α (TNF-α), interleukin-6 (IL-6), interferon-γ (IFNγ)], as well as in the pro-inflammatory/anti-inflammatory ratios of TNF-α/IL-10 and IL-6/IL-10 in PSD subjects after 1, 3, 6, 9, and 12 months of stroke (64). The gene discussed is TNF; the disease is stroke disorder.