IL17A and Huntington disease: IL17 has been found to be secreted by astrocytes within the brain51, however we failed to detect Il17 gene expression in either WT or R6/2 mice in our qPCR analysis which might suggest a minimal role of these glial cell population to the observed cytokine upregulation in the HD brain, since they are also coincidently capable of secreting cytokines such as TNFα52.