HMGA2 and neoplasm: It is overexpressed in many human solid tumors and its upregulation was thought to be potentially associated with tumor progression and poor prognosis.32,33 This study reports the strong negative prognostic impact of HMGA2 overexpression in AML, thus justifying the development and validation of a rapid, simple and inexpensive RT-qPCR test, also optimized on the droplet digital PCR platform, which can now be implemented in clinical laboratories.