In line with this, mTOR-dependent impairment of autophagy is implicated in various neuropsychiatric disorders such as dementia, movement disorders, motor neuron disease, seizures, brain ischemia, autism, affective disorders, addiction, and schizophrenia [45,46,47,48,49,50,51,52,53,54,55,56,57]. This evidence concerns the gene MTOR and brain ischemia.