Thus, we further investigated the association of LINC00675 expression with TRIP6 mRNA and protein in glioma tissues and cells, and found that levels of LINC00675 expression were positively correlated with TRIP6 mRNA and protein expressions, and silencing of LINC00675 dramatically inhibited TRIP6 mRNA and protein expressions in glioma cell. This evidence concerns the gene TRIP6 and central nervous system cancer.