Some of the genes involved in innate immunity were up-regulated in the tumor samples, including Tlr3, Clec7a, Isg20, Csf1, Irf7, and Lgals3. Genes involved in immune response including the Major Histocompatibility Complex (MHC) class II antigen presentation as exemplified by H2-Aa, H2-Ab1, and H2-Eb1 genes were up-regulated. The gene discussed is TLR3; the disease is neoplasm.