Interestingly, CD3+ T cell and CD11b+ granulocytes were found to be present only in the hepatitis group, but not in the tumor and control group (Supplementary Figure S1), thus, this excluded the possibility that the up-regulation of immune/inflammatory-related genes in the tumors were caused by the immune cell infiltration into the harvested tumor tissues. Here, ITGAM is linked to hepatitis A virus infection.