ALCAM and non-small cell lung carcinoma: We have recently identified and characterised a novel double positive (CD166+/CD44+ and CD166+/EpCAM+) CSC sub-population isolated from NSCLC cell lines (A549 and H2170), and showed that these two sub populations exhibit a self-renewal capacity, higher mobility, resistance to apoptosis, and the ability to differentiate towards the mesenchymal lineage [140].