This is consistent with our preliminary data suggesting that the number of these cells before transplant predicted acute rejection only in kidney transplant recipients receiving costimulation blockade-based immunosuppression with CTLA4Ig (Cravedi P, Gandolfini I, Donadei C, et al. Pre-Transplant Panel Reactive T Cells (PRT) with IL-15 as a Risk-Stratifier of Acute Rejection in Kidney Transplant Patients on Belatacept Therapy. The gene discussed is IL15; the disease is medical procedure.