IGHE and airway hyperresponsiveness: An interesting finding in this study was that plant encoding hypoallergen Per a 2–372 consistently gave better effects in terms of inhibition of development of allergen-specific IgE production, airway hyperresponsiveness, type 2 cytokine production, as well as inhibition of lung inflammation, in comparison with the effects of plant encoding full-length allergen Per a 2–996.