The cliques involving AKT1 (METH), PTEN (mRNA) and AKT1 (METH), PIK3R2 (mRNA) can be construed as tumor suppressing, while cliques involving AKT1 (METH), CCND1 (mRNA) and AKT1 (METH), GRB2 (CN) probably are tumor activating. Here, PTEN is linked to neoplasm.