When we examined all non-hematopoietic cancer cell lines in the CCLE, we found that the degree of FLNB exon 30 splicing correlated significantly with a ZEB1 target signature, an epithelial differentiation signature, two metastasis signatures and a mammary stem cell signature (Figure 5B and Figure 5—figure supplement 1C). The gene discussed is ZEB1; the disease is cancer.