The presence of a concurrent response to the immunodominant antigens ESAT‐6/CFP‐10 indicates infection with an RD‐1 positive MTBC mycobacteria (i.e., excludes infection with M. microti or previous vaccination with M. bovis‐BCG) (Guinn et al., 2004; Teo et al., 2013). The gene discussed is PDE6B; the disease is infection.