VTCN1 and hepatocellular carcinoma: We found the negative regulator of T-cell response, V-set domain-containing T-cell activation inhibitor 1, VTCN1, (also named as B7-H4, B7S1, or B7x) was aberrantly expressed in HCC patients in the high-risk group and B7-H4 positivity was a statistically significant predictor of poor overall survival and recurrence-free survival.