The findings of our research are in accordance with previous studies demonstrating the effect of MIF on the ACS and atherosclerosis [13, 18, 19, 31, 32] and with the other research published by Van der Vorst et al. that showed that serum MIF levels in cardiovascular disease (CDV) patients were associated with inflammatory markers like CRP and IL-6 and also as a high independent risk factor for future coronary events in patients with CVD [34]. Here, IL6 is linked to atherosclerosis.