We conclude that altered p53 and nuclear WT1 expression combined was associated with reduced survival after adjusting for both age and tumour subtype as well as age and FIGO stage, and that nuclear WT1 expression was a biomarker for lethal OvCa and that OvCas expressing WT1 are more frequently lethal when p53 is also altered. The gene discussed is TP53; the disease is neoplasm.