TP53 and neoplasm: As suggested by 'REporting recommendations for tumour MARKer prognostic studies(REMARK)'26 we first studied the 137 ovarian tumours in our data set for standard prognostic variables including histopathologic subtype, tumour grade and stage of disease (Table 1B and Fig. 1b) for comparison to the proposed prognostic biomarkers of survival, namely altered immunohistochemically detected p53 and WT1 nuclear expression.