NR3C2 and Schnyder corneal dystrophy: However, although they were increasingly used as a usual ‘routine’ care in the compared arms of the more recently published clinical trials,58 BBs stayed underused for long time and may still be.59 Mineralocorticoid receptor antagonists or antialdosterone drugs have been reported effective in HFrEF by reducing SCD and all-cause mortality.21 22 54 60 Our summary of the findings and the consistency of the results support this claim with a high quality of evidence.