Using univariate analysis, we found that the significant risk factors for diabetes mellitus according to the highest versus the lowest quartiles included BMI, waist circumference, waist to hip ratio, systolic blood pressure, diastolic blood pressure, glycosylated hemoglobin A1c (HbA1c), glucose, IRI, HDL-C, TG, non-HDL-C, and LCAT activity. The gene discussed is LCAT; the disease is diabetes mellitus.