However, in the analysis performed on men and women separately, we found a significant association between baseline LCAT activity and the future risk of diabetes mellitus only in men (RR 9.15; 95% CI, 1.02–81.95; P = 0.048 for men and RR, 2.67; 95% CI, 0.47–15.41; P = 0.27 for women). This evidence concerns the gene LCAT and diabetes mellitus.