Furthermore, LRRK2 and Rab29/Rab7L1 control the integrity of the endolysosomal protein degradation process in a common pathway that is affected by PD-linked mutations (Fujimoto et al., 2018, MacLeod et al., 2013, Puriyte et al., 2018, Zhiyong et al., 2018). Here, LRRK2 is linked to Parkinson disease.