In our differential expression analysis between the IL17AHi and the IL17ALo producing CD8+ T cells, we found that TMPRSS11D and PM20D1 were down-regulated in the IL17AHi, which Suarez-Farinas et al. 41 observed to be down-regulated in lesional psoriasis skin versus healthy control skin. The gene discussed is CD8A; the disease is psoriasis.