HBEGF and neoplasm: Selective conditional ablation of the FAP+ TAM population in an immunogenic ovalbumin (OVA)-expressing LL2 tumour using diphtheria toxin in bone marrow chimeric FAP/diphtheria toxin receptor transgenic (DTR Tg) mice, resulted in an immunological control of tumour growth demonstrating that this macrophage subset played an important role in immune suppression3,15.