KLHL42 and type 2 diabetes mellitus: Nevertheless, it is noteworthy that there are three T2D-associated variants at the CAMK1D/CDC123, ADCY5, and KLHDC5 loci that show hypomethylation and allelic imbalance as identified by Thurner et al.42 using WGBS data (n = 10), all of which were genome-wide significant in our mQTL-based SMR analysis.