We then evaluated specific IgG responses to multiple antigens from the following infections and vaccines: (i) seven common persistent pathogens, including five viruses: CMV, EBV (EA, EBNA, and VCA antigens), herpes simplex virus 1 and 2 (HSV-1 & 2), varicella zoster virus (VZV), one bacterium: Helicobacter pylori (H. pylori), and one parasite: Toxoplasma gondii (T. gondii); (ii) one recurrent virus: influenza A virus (IAV); and (iii) four viruses for which most donors received vaccination: measles, mumps, rubella, and HBV (HBs and HBc antigens). This evidence concerns the gene KRT88P and infection.