TP53RK and Galloway-Mowat syndrome: Recently, Hildebrandt and colleagues [11] identified novel causative mutations in the genes encoding the four KEOPS (Kinase, Endopeptidase and Other Proteins of small Size) subunits, OSGEP, TP53RK, TPRKB, and LAGE3, in 37 individuals from 32 families with GAMOS.