ACHE and early-onset autosomal dominant Alzheimer disease: Over the past three decades, many specific alkaloids have been isolated (galanthamine, lycorine, crinine, haemanthamine, tazettine, narciclasine etc.)and reported to have acetylcholinesterase inhibitory effect (for the treatment of Alzheimer’s disease), antiviral, antibacterial, antifungal, antimalarial, antitumor and cytotoxic activities [3, 6–10].