When CRP or BASMI was added to model 2 (again as a sensitivity analysis), they were not associated with improvement in ASQoL [0.11 (95% CI −0.47, 0.69) and −0.01 (95% CI −0.07, 0.06), respectively] and neither was HADS (anxiety) [severe anxiety −0.79 (95% CI −4.13, 2.55)] or HADS (depression) [severe depression −3.29 (95% CI −7.48, 0.91)]. The gene discussed is CRP; the disease is major depressive disorder.