In contrast, FBXO2 was undetectable in four gastric cancer cell lines we examined, including EBV-positive AGS cell line, it might because of the different cancer types, as most gastric tumors are adenocarcinoma, while more than 90% of all oral cancers are squamous cell carcinoma, and the majority of NPCs are the undifferentiated carcinoma. Here, FBXO2 is linked to undifferentiated carcinoma.