The difference in PDGF-CC expression between control and the respective tumour tissue was evaluated using a modified H-Score system [34] revealing increased PDGF-CC expression in epithelial tissues of bladder (p = 0.039), brain gliosarcoma (p<0.001), breast infiltrating ductal carcinoma (p = 0.006), renal cell cancer (p = 0.008), colon (p<0.001), pancreas (p<0.001) and prostate adenocarcinoma (p = 0.001) (Table 5). Here, CXCR1 is linked to renal cell adenocarcinoma.