CTNNB1 and hepatocellular adenoma: There are 3 major molecular classifications of HCA: (a) β-catenin (CTNNB1)-activated HCA (B-HCA), (b) hepatocyte nuclear factor 1 α (HNF1α)-inactivated or steatotic HCA (H-HCA), and (c) inflammatory HCA (I-HCA) [6, 8, 9].