SPG11 and amyotrophic lateral sclerosis: Juvenile‐onset ALS is associated with the great majority of the kindreds, with both autosomal recessive and autosomal dominant pattern of inheritance (Conte et al., 2012), and mutations in several genes such as alsin (ALS2), SETX, spatacsin (SPG11), SOD1 (Orban, Devon, Hayden, & Leavitt, 2007), and FUS (Belzil et al., 2012; Conte et al., 2012; Zou et al., 2013).