The results showed that PGC1β infection (NBL/↑PGC1β) significantly increased mRNA expression of PGC1β and LDHA compared to the NBL control (NBL/CTL) group, while PGC1β lentivirus knockdown in CD138+ cells (CD138 + /shPGC1β) significantly decreased the expression of PGC1β and LDHA compared to the CD138+ control (CD138 + /CTL) group. This evidence concerns the gene PPARGC1B and infection.